HORDB

ID: hor002674
Uniprot ID: Q20017
Protein name: NLP-5
Gene name: nlp-5
Organism: Caenorhabditis elegans
Family: NA
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: NA

Sequence: SVSQLNQYAGFDTLGGMGL
Length: 19(44-62)
Propeptide: MLMKIMVLMGIANIAASFVVSSVRFQSAPMRALIEINRELAKRSVSQLNQYAGFDTLGGMGLGKRSEPDQAGEKRALSTFDSLGGMGLGKRSSSSSRVFVYDKRALQHFSSLDTLGGMGFGRK
Signal peptide: MLMKIMVLMGIANIAAS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002674_AF2.pdb

hor002674_ESM.pdb

Mass:	227943	Formula:	C85H132N22O29S
Absent amino acids:	CEHIKPRW	Common amino acids:	G
pI:	3.75	Basic residues:	0
Polar residues:	9	Hydrophobic residues:	6
Hydrophobicity:	15.26	Boman Index:	-625
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	82.11
Instability Index:	2921.58	Extinction Coefficient cystines:	1490
Absorbance 280nm:	82.78

PubMed ID: 20013198
Title: Approaches to Identify Endogenous Peptides in the Soil Nematode Caenorhabditis elegans